In order to achieve this, nine selected microRNAs (let-7b, miR-18a, miR-18b, miR-106b, miR-25, miR-29c, miR-375, miR-424, miR-505) were tested by qPCR in total RNA isolated from 204 new LN- breast cancers patients under the age of 71 and investigated correlations with classic clinicopathological features like proliferation (measured by MAI, PPH3 and Ki67), ERα, progesteron receptor (PR), Her2, and CK5/6. The gene discussed is ERBB2; the disease is breast carcinoma.