CCND1 and mantle cell lymphoma: Experimental data supporting the functional role of the 3′-UTR region in the expression of CCND1 have been reported in mantle cell lymphomas (MCL), where in addition to the fusion of CCND1 gene on chromosome 11 to the immunoglobulin heavy chain enhancer, the loss of the 3′-UTR has been linked to hyper-proliferative MCL [36].