Our HIV-infected cohort was predominantly male (95.5%), relatively young (median age 36.4 years, interquartile range (IQR) 28.1–43.6), racially and ethnically diverse (48.5% White, 29% Black, 14.0% Hispanic, and 8.5% other race/ethnicity), well educated (34% with post-secondary degree), had few comorbidities (only seven reported current illicit drug use and three had hepatitis C), and healthy (median CD4 count: 546 cells/mm3, IQR 417–706) with 64% receiving ART. This evidence concerns the gene CD4 and hepatitis C virus infection.