The Th1-derived cytokine IP-10 after FASCIA and multiplex analysis is an interesting biomarker, as are the other Th1- cytokines, with very high sensitivities in Mtb infection, and a high specificity compared to controls with no exposure to Mtb. They could possibly be used, after setting adequate cut-offs for active TB and LTBI, to differentiate between different clinical entities of Mtb infection. Here, NELFCD is linked to tuberculosis.