Compared to controls, the cytokines IFN-γ, IP-10, IL-2, TNF-α, MIP-1β, GM-CSF, IL-13 and IL-6 were produced significantly more often in higher amounts (p<0.05 with the Kruskal Wallis and Wilcoxon's rank sum test) in samples from patients with active TB after stimulation with ESAT-6 and CFP-10 (Table 3). This evidence concerns the gene IFNG and tuberculosis.