PLA2G7 and hyperinsulinemic hypoglycemia, familial, 4: According to a 1999 study by Stafforini et al. PAF-AH/Lp-PLA2 deficiency was increased in asthmatics in comparison with healthy subjects in Japan with the greatest asthma severity found in homozygous PAF-AH/Lp-PLA2 deficient subjects [25].