In summary, FSHR with completely wild-type homozygous SNPs at positions 307 and 680 (307Thr/Thr680Asn/Asn) had higher sensitivity to FSH and an increased risk of endometriosis, whereas FSHR possessing at least an allele of mutant SNP at positions 307 and 680 lower risk of endometriosis. This evidence concerns the gene FSHR and endometriosis.