HSD17B3 and endometriosis: A combination of homozygous/heterozygous mutants of HSD17B3 (genotype AA+AG, 289Ser/Ser+289Ser/Gly) and homozygous/heterozygous mutants of FSHR (genotype GG+GA, 680Ser/Ser+680Ser/Asn) was associated with a significantly decreased risk of endometriosis (P = 0.00002) in comparison with the combination of homozygous wild-type SNPs of HSD17B3 and FSHR(Table 4).