Collectively, the GG homozygous genotype of polymorphism of HSD17B3 (289Gly/Gly) (wild type) may play a crucial role in the development of endometriosis in the presence of AA homozygous genotype of polymorphism of FSHR (680Asn/Asn) (wild type). Here, HSD17B3 is linked to endometriosis.