LMNA and Alzheimer disease: Following are some of such diseases: autosomal dominant form of EDMD (EDMD2, AD-EDMD; OMIM 181350) [23] autosomal recessive EDMD (EDMD3, AR-EDMD; OMIM 604929), cardiomyopathy dilated 1A (CMD1A; OMIM 115200) [31], limb-girdle muscular dystrophy type 1B (LGMD1B; OMIM 159001) [165] congenital-type muscular dystrophy (OMIM 613205) [158] and “heart-hand” syndrome (HHS; OMIM 610140) [198] All mentioned diseases are caused by the mutations in LMNA gene, and have different clinical phenotypes.