ERBB2 and neuroblastoma: The role of EGFR in the proliferation of NB, and the utility of its inhibitors in the treatment of NB, have all been well documented; however, the data remain somewhat contradictory (16,17), as other reports have demonstrated that exposure to EGF can induce apoptosis in NB through the ERBB2 and ERBB3 receptors (18–20).