In vitro experiments revealed that enhanced immunoreactivity of MRP2 could confer to cancer cell lines (including ovarian cancer) chemoresistance to platinum-containing anticancer drugs (cisplatin and carboplatin) and non-platinum-containing drugs, including methotrexate, vinblastine, and camptothecin derivatives [25–27]. The gene discussed is ABCC2; the disease is ovarian carcinoma.