CDKN2B and type 2 diabetes mellitus: In this genomic region near the protein-coding genes CDKN2A and CDKN2B containing two adjacent linkage disequilibrium (LD) blocks the two single nucleotide polymorphisms (SNPs), rs10811661 and rs10757278, were consistently replicated as having an independent association with T2D and CVD, respectively[5,7,8].