In contrast to tissue invasive helminth infection, malaria is characterized by an acute inflammatory response with increases in serum proinflammatory cytokine and chemokine levels, including IL-1β, IL-6, IL-8, TNFα, IP-10, IL-1ra and IL-12p70 [8], [9], [10], [11], [12], [13], [14]. This evidence concerns the gene CXCL8 and malaria.