SELENOS and neoplasm: Regardless of markers of Se status, when tumour grade and disease stage were taken into account in the analysis there was a trend towards reduced risk of a high grade tumour in individuals carrying at least one T allele for rs28665122 in the gene SEPS1 (OR = 0.57, 95% CI = 0–31–1.06, p = 0.08) (Table 3).