Like other pathogenic E. coli strains, EAggEC strains are susceptible to infection by lambdoid phages including stx phages: a report of a 2001 case of HUS caused by a stx2-positive EAggEC belonging to the O104:H4 serotype [28], [29] was followed in 2009 by several cases of HUS and bloody diarrhea cases in the Republic of Georgia, which were eventually attributed to strains of stx2-positiveE. Here, STX2 is linked to hemolytic-uremic syndrome.