For example, levels of FANCE (Fanconi anemia, complementation group E) expression is significantly associated with rs1516982 (permutated P = 8.0×10−4, adjusted r2 = 10.3%), rs10098821 (permutated P = 0.0037, adjusted r2 = 7.0%) and rs10088218 (permutated P = 0.0312, adjusted r2 = 3.4%), but none of the other four SNPs (Figure S2). Here, FANCE is linked to Fanconi anemia.