EZH2 and breast carcinoma: When pairing the primary breast carcinoma with its metastatic focus/foci, there was a significant enrichment for equivalent or increased EZH2 expression versus decreased expression, with six (6) pairs having decreased EZH2 expression at the metastatic focus (7%), 43 pairs having equivalent expression (52%), and 33 pairs having increased expression (40%) (p<0.0001).