In the case of Ki67-IR, there appeared to be two peaks of with approximately equal significance levels, and in consequence the highest points of significance were taken for both peaks, to give three tranches: <1.5, 1.5–2.9 and ≥3 (scores represent the number of tumour cells positive for this biomarker in crossing 11 horizontal lines across the core, Fig. 3C). The gene discussed is MKI67; the disease is neoplasm.