In the present study we found that there was a high correlation between tumour pAkt-IR and pEGFR-IR scores, confirming the study of Koumakpayi et al. [17], and consistent both with the finding of a high (54%) co-expression of EGFR and pAkt in prostate tumour cells [10] and the known signalling interrelationship between these two parameters [19]. The gene discussed is EGFR; the disease is prostate neoplasm.