Since we knew from the literature that ML can stimulate immune effector cells and since we have seen that the secretion of TGF-β, the most important immunosuppressive cytokine in glioma, is decreased after treating the cells with ISCADOR Q (Figure 1), we asked whether ISCADOR might induce immune cell mediated GBM cell attack, too. Here, TGFB1 is linked to central nervous system cancer.