To further elucidate the role of CFTR mislocalization in the aberrant ductal HCO3- secretion in chronic pancreatitis, we have examined histology (Mizuno et al., 2009) and exocrine functions of patients with autoimmune pancreatitis at the diagnosis and 3 months after maintenance steroid treatment (Ko et al., 2010). Here, CFTR is linked to autoimmune pancreatitis.