MC4R and type 2 diabetes mellitus: We analyzed the interaction between folate intake (as dichotomous based on the population mean of 406 μg/d) and the polymorphisms on type 2 diabetes, but we did not obtain any statistically significant interaction term (P-interaction=0.203 for the FTO rs9939609, P-interaction=0.745 for the MC4R rs17782313 and P-interaction=0.667).