IFNA2 and thymoma: An interesting point of contact between APS-1 and thymomas is the presence of circulating Abs to various cytokines, such as interferons (IFNs) and interleukins (ILs): in the original article of Meager et al., sera from APS-1 patients showed high-titer neutralizing Abs to type-1 IFNs such as IFN-α, all subtypes included, and IFN-ω; IFN-β, another member of type-1 IFNs, as well as IFN-λ1, a subtype of type-3 IFNs, were less frequently targeted [80].