Similarly, Trabedersen (AP 12009) is a phosphorothioate antisense oligodeoxynucleotide specific for human TGFβ2 mRNA with antitumour activity in human pancreatic cancer, such as reduction in tumour growth, lymph node metastases, and angiogenesis [17]. This evidence concerns the gene TGFB2 and familial pancreatic carcinoma.