AKT1 (7.82 (2.61–11.45)), MAPK1 (19.47 (8.71–33.45)), and ZAP70 (1.98 (1.14–3.66)) relative gene expressions levels were significantly augmented in PBMC from SLE patients (n = 13) as compared with controls (Wilcoxon Signed Rank test: P = 0.0064, P = 0.0012, and P = 0.0024, resp). This evidence concerns the gene MAPK1 and systemic lupus erythematosus.