To assess whether BSP expression correlated with clinicopathological characteristics other than tumor grade, we did a correlation analysis and found that high BSP expression correlated with older age (P = 0.007), absence of seizure (P = 0.001), and astrocytic tumor lineage (P = 0.003), but did not correlate with any other clinicopathological parameters (Table S1). This evidence concerns the gene IBSP and neoplasm.