Interestingly, overexpression of PDGFR-α expression in breast cancer has previously been associated with lymph node metastasis (P = 0.0079) in a cohort of 181 invasive ductal breast carcinomas patients [13] suggesting that PDGFA may be clinically relevant for breast cancer lymph node metastasis. This evidence concerns the gene PDGFRA and metastatic malignant neoplasm in the lymph nodes.