Significantly lower NAA/Cr, Cho/Cr and NAA/Cho were found in the patients with MSA-C than those with SCA6, except for NAA/Cho in the cerebellar hemispheres (p = 0.086) and NAA/Cr in the vermis (p = 0.185). Here, CACNA1A is linked to multiple system atrophy, cerebellar type.