HMOX1 and chronic hepatitis: The total HO-1-IHC OD per volume (Figure 6) in the rats with chronic hepatitis was significantly increased at d28 (1.6-fold), d56 (2-fold), and d84 (3-fold) compared with that at d0, respectively (P < 0.01); these at d56 and d84 significantly increased compared with that at d28, respectively (P < 0.01); so did that at d84 compared with that at d56 (P < 0.01).