Our results agree with the findings of Peck and colleagues [5] that showed that deletion of IFN-γ and IFN-γ-receptor genes in the susceptible NOD mouse strain reversed the lymphocytic infiltration of the submandibular glands and the salivary secretory dysfunction, but had no effect on the severity of lacrimal gland disease [5]. The gene discussed is IFNG; the disease is disorder of lacrimal gland.