MGP and melanoma: Immunohistochemistry analysis of cryopreserved tissue sections, prepared from normal skin, atypical nevi, which are the precursors and risk markers of melanoma, MIS, and advanced melanomas, with an antibody to human DDX11 revealed strong expression of DDX11 in advanced melanoma comprised of VGP and MGP melanomas and melanoma-infiltrated lymph nodes (LN) (Figure 1A).