The known resistance of ATC to classical chemotherapies could be explained by the presence of a large proportion of CSC-TPC like cells in the tumor and by the increased expression in our data of mRNAs encoding multidrug resistance proteins such as some ATP-binding cassette family members (ABCA8, ABCB10, ABCC5, ABCC10, ABCG1). The gene discussed is ABCB10; the disease is neoplasm.