This includes a model for Aβ induced pathology (Sofola et al., 2010; Rogers et al., 2012), models for polyQ diseases (Spinobulbar muscular atrophy (SBMA; Pandey et al., 2007), and SCA3 (Martin-Lannerée et al., 2006), model for Parkinson disease (Kanao et al., 2010) as well as the two FTD models used in this study (FUS and TBP43; Lanson et al., 2011; Miguel et al., 2011, 2012). Here, FUS is linked to Parkinson disease.