These studies have demonstrated that decreasing the tissue ratio of n−6/n−3 can significantly reduce the formation and growth of various cancers, which is associated with reduced levels of cancer-related eicosanoids and genes [41]–[48], suggesting that the tumor-promoting effect of increased D6D activity can be diminished by decreasing tissue n−6/n−3 fatty acid ratio. Here, FADS2 is linked to neoplasm.