Within the different grades of HCC; the sensitivities of arginase-1 in well, moderately, and poorly differentiated HCCs are 100%, 90%, and 44.4%, respectively, whereas, in comparison, HepPar-1 demonstrated sensitivities of 100%, 73.3%, and 22.2% for well, moderately, and poorly differentiated tumors, respectively. The gene discussed is ARG1; the disease is hepatocellular carcinoma.