For example, mutation in SLIT and NTRK-like 1 (SLITRK1) can cause TS, and though there are other examples, each only accounts for a small fraction of cases [8,9] Notably, our previous study discovered a set of specific alternatively spliced genes that differentiate TS from controls, suggesting that there may be a shared molecular pathophysiology common to many subjects with TS [10]. The gene discussed is SLITRK1; the disease is Timothy syndrome.