EZH2 and synovial sarcoma: Although high EZH2 expression was shown to be generally associated with poor prognosis in soft tissue sarcomas[13], neither differential expression of EZH2 in the various histological subtypes of synovial sarcoma nor the association of EZH2 with H3K27 trimethylation, tumor behavior, and clinical parameters has been investigated in this particular tumor type.