EZH2 and neoplasm: Since synovial sarcoma patients are divided into low-risk and high-risk prognostic groups based on age (younger or older than 25 years), tumor size (larger or smaller than 5 cm), mitotic activity, and the presence or absence of poorly differentiated areas[3,14], correlations were sought between EZH2 expression and these prognostic factors, as well as with other clinical data such as gender, tumor location, distant metastasis, and the type of fusion gene which also has been reported to impact disease outcome[15].