Another class of proteins of interest in relation to novel biomarkers are the targets of type I diabetes autoimmune antibodies and suggested potential biomarkers include glutamic acid decarboxylase enzyme (GAD65), islet cell antigen 512 (IA-2) and zinc transporter 8 (ZnT8)[2,98-100,102]. The gene discussed is PTPRN; the disease is Autoimmunity.