IGHG3 and infection: Thus, to gain additional insights in the differential antibody response generated in the Asy and Sym individuals under natural infection conditions, we measured IgG1 and IgG3 responses for PfRh2a, PfRh2b, PfRh5 and EBA-181, for which a higher total IgG response was observed to be negatively correlated with lower parasitaemia (Figure 2).