HuR binding has been shown to enhance the stability of mRNAs involved in proliferation [57-59], while also playing a role in breast cancer, as cytoplasmic accumulation of HuR promotes tamoxifen resistance in BT-474 cells [60] and the stability of HER2/ERBB2 transcripts in SK-BR-3 cells [52]. This evidence concerns the gene ELAVL1 and breast carcinoma.