PLA2G6 and Insulin resistance: In a rat model of intracerebroventricular streptozotocin-induced brain insulin resistance and hypoglycemia, cerebral cortex concentrations of ethanolamine glycerophospholipid (EtnGpl) and phosphatidylserine (PtdSer) were decreased, while concentrations of unesterified palmitate, stearate and AA were increased, suggesting increased PLA2-mediated membrane degradation [11,12].