In recent years, however, a number of reports have identified Treg specific for a range of tumor antigens in human cancer, including NY-ESO-1, survivin, TRP-1, gp100, MAGE-A3, Melan-A, carcinoembryonic Ag (CEA), telomerase, HER2/neu, WT-1, MUC-1 and papillomavirus antigens E6 and E7 [10]–[16]. This evidence concerns the gene ERBB2 and neoplasm.