IL4 and malaria: In this study, we aim to investigate the contribution of three functional IL-4 polymorphisms rs2243250 (-590 C>T, promoter), rs2070874 (-34 C>T, 5′UTR) and rs79071878 (intron-3, 70 bp VNTR) with P. falciparum malaria infection in well-defined malaria cases and in ethnically matched controls.