In line with the key processes identified by the pathway analysis, these genes had a range of functions including regulation of cell growth and proliferation and cancer development (PSAT1, Hint, SDCCAG10, p53 and C-myc), cell cycle (Ube2c, Hint, GMPS and p53), apoptosis (Hint), protein synthesis and folding (SDCCAG10, TOMM34, eEF1G), cardiac muscle growth (USMG5) and developmental processes (TBX3, FGFR1). This evidence concerns the gene HINT1 and cancer.