MALAT1 and urinary bladder carcinoma: Schmidt et al. (2011) showed that decreased expression of MALAT1 in NSCLC xenografts led to impaired tumor formation and growth. These reports suggested that MALAT1 is a potent player in the metastasis process. In other types of cancer cells, such as CaSki cervical cancer cells, MALAT1 is involved not only in cell migration, but also in cell growth and cell cycle progression (Guo et al., 2010). Another report demonstrated that MALAT1 promotes epithelial-to-mesenchymal transition (EMT) by activating the Wnt/β-catenin pathway in bladder cancer cells (Ying et al., 2012).