Kobayashi et al. [95] concluded that “EGFR-TKI using erlotinib may be an alternative option for patients resistant to cytotoxic chemotherapy, even in those with EGFR wild-type NSCLC” based on the results from a phase II clinical trial in patients carrying wild type EGFR (Table 4). Here, EGFR is linked to non-small cell lung carcinoma.