GPT and Hyperbilirubinemia: Enlargement >3 cm below the costal margin at the mid clavicular line, confirmed by ultrasound or dysfunction documented by: hyperbilirubinemia >3 times normal hypoalbuminemia (<30 g/dl), γ GT increased >2 times normal, ALT (SGPT)–AST (SGOT) >3 times normal, ascites, edema, or intra hepatic nodular mass