HMOX1 and atherosclerosis: In the context of atherosclerosis, a population of macrophages expressing a unique set of genes including Heme oxygenase-1 (HO-1), sufiredoxin-1, and thioredoxin-reductase in a nuclear factor, erythroid-derived 2, like 2(Nrf2) dependent manner was found within the aortas of 30 week western diet-fed Ldlr−/− mice by immunohistochemistry and flow cytometry.