Likewise, CYP11B1 and CYP11B2 are decreased by azelnidipine, benidipine, and efonidipine (* in Figure 1) in NCI-H295R human adrenocortical carcinoma cells [18–20], while efonidipine increases DHEA-S production in NCI-H295R human adrenocortical carcinoma cells probably as a result of increased StAR expression (# in Figure 1) [22]. The gene discussed is CYP11B1; the disease is adrenal cortex carcinoma.