TNF and meningeal tuberculosis: The final multivariate logistic regression model included IFN-γ and TNF-α and produced a cross-validated AUC of 0.91 (95% CI, .53–.99, P = .02), indicating high diagnostic accuracy when jointly considering these 2 cytokines to differentiate TBM-IRIS from non-TBM-IRIS at time of TBM diagnosis.