Moreover, a meta-analysis showed that patients with one of single nuclear polymorphisms vitamin D receptor (VDR), the FokI rs2228570 TT genotype, had a significantly higher risk for developing ovarian cancer as well as prostate, breast, skin, non-Hodgkin lymphoma, and colorectal cancer compared with its CC genotype[19,20]. The gene discussed is VDR; the disease is colorectal cancer.