S100A8 and neoplasm: Expressing CagAEPISA in whole eye clones also did not produce an invasive phenotype (Figure S5C), and coexpression of CagAEPISA with RasV12 caused a less pronounced enhancement of the mild invasion caused by expression of RasV12 alone (Figure 5C), suggesting that the phosphorylation-resistant form of CagA is less effective at promoting tumor progression.