No effects of cholesterol or sitostanol were found on the production of Th2 cytokines IL-4 and IL-13 in either asthma patients or controls, with the only exception for sitostanol, which tended to decrease IL-13 production in the control group when compared to the cyclodextrin condition (−268 pg/ml p = 0.093). The gene discussed is IL13; the disease is asthma.